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Hyojik Jung

As seen in: Nature, MDPI
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Articles

Establishment of Canine Transitional Cell Carcinoma Cell Lines Harboring BRAF V595E Mutation as a Therapeutic Target

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By Hyojik Jung, Kieun Bae, Jung-Hyun Kim, Ja Young Lee
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited.
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A fusion of CD63-BCAR4 identified in lung adenocarcinoma promotes tumorigenicity and metastasis

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By Kieun Bae, Jin Kim, Kyong-Ah Yoon, Hyojik Jung
| Nature Verified
Abstract Background Recently, fusion variants of the breast cancer anti-oestrogen-resistance 4 (BCAR4) gene were recurrently discovered in lung adenocarcinoma from the genome-wide studies. However, the functional characterisation of BCAR4 fusion has not been investigated. Methods Based on the analysis of RNA-sequencing data, we identified a fusion transcript of CD63–BCAR4 in a Korean patient with lung adenocarcinoma who did not harbour any known activating mutations in EGFR and KRAS genes.
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