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Hyun Myung Doo

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Articles

Plasma biomarkers in ischemia and reperfusion in acute occlusion of the superior mesenteric artery: a rat model study

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By Hyokee Kim, Chinock Cheong, Sun-Young Ko, Bo-Hyung Lee, Won Jun Seo, Hyun Myung Doo
| Nature Verified
Abstract Acute mesenteric ischemia (AMI) remains a life-threatening condition with high mortality rates due to the lack of sensitive biomarkers for early diagnosis. We investigated phase-specific biomarker profiles using a Sprague–Dawley rat model of superior mesenteric artery occlusion to distinguish between ischemic and reperfusion injuries. Rats were assigned to control, ischemia (1 h clamping), and reperfusion (1 h ischemia followed by 2 h reperfusion) groups.
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