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Hyungchul Jung

As seen in: BioRxiv
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Articles

The somatic mutation landscape of normal gastric epithelium

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By Tim H.H. Coorens, Grace Collord, Yichen Wang, Hyungchul Jung
| BioRxiv
Abstract The landscapes of somatic mutation in normal cells inform on the processes of mutation and selection operative throughout life, permitting insight into normal ageing and the earliest stages of cancer development. Here, by whole-genome sequencing of 238 microdissections from 30 individuals, including 18 with gastric cancer, we elucidate the developmental trajectories of normal and malignant gastric epithelium.
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