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Iêda Maria Begnini on Muck Rack

Iêda Maria Begnini

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Efflux Pump (QacA, QacB, and QacC) and β-Lactamase Inhibitors? An Evaluation of 1,8-Naphthyridines against Staphylococcus aureus Strains

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By Saulo Relison Tintino, Priscilla Ramos Freitas, Ricardo Rebelo, Iêda Maria Begnini
| MDPI
Abstract : The bacterial species Staphylococcus aureus presents a variety of resistance mechanisms, among which the expression of β-lactamases and efflux pumps stand out for providing a significant degree of resistance to clinically relevant antibiotics. The 1,8-naphthyridines are nitrogen heterocycles with a broad spectrum of biological activities and, as such, are promising research targets.
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