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Iganzio Avella on Muck Rack

Iganzio Avella

As seen in: BioRxiv
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Articles

A genome-guided atlas to the composition, activity, and β-bungarotoxin dimerization in many-banded krait venom inferred by functional venomics

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By Lilien Uhrig, Lennart Schulte, Sabine Hurka, Iganzio Avella
| BioRxiv
Abstract Snakebite is a neglected tropical disease claiming ~140,000 lives every year. One of the most medically relevant snakes of Asia is the many-banded krait (Bungarus multicinctus). Approximately 8% of the global human population is at risk of being envenomated by this species, able to cause fatal neurotoxicity. Here, we present a proteogenomic and functional assessment of the B.
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