Igor Chernyavsky on Muck Rack

Igor Chernyavsky

As seen in: European Respiratory Journal
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Articles

In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss

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By Igor Chernyavsky, Richard Russell, Ruth Saunders, Rachid Berair
| European Respiratory Journal Verified
In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss Igor L. Chernyavsky, Richard J. Russell, Ruth M. Saunders, Gavin E. Morris, Rachid Berair, Amisha Singapuri, Latifa Chachi, Adel H. Mansur, Peter H. Howarth, Patrick Dennison, Rekha Chaudhuri, Stephen Bicknell, Felicity R.A.J. Rose, Salman Siddiqui, Bindi S. Brook, Christopher E. Brightling European Respiratory Journal May 2018, 51 (5) 1701680; DOI: 10.1183/13993003.01680-2017
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In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss

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By Igor Chernyavsky, Richard Russell, Ruth Saunders, Gavin Morris
| European Respiratory Journal Verified
AbstractBronchial thermoplasty is a treatment for asthma. Whether during thermoplasty the airway wall fraction exposed to temperatures necessary to affect cells is sufficient to explain its histopathological impact is unclear.Airway smooth muscle and bronchial epithelial cells were exposed to media (37–70°C) for 10 seconds to mimic thermoplasty. In silico we developed a mathematical model of airway heat distribution following thermoplasty.
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ASM behaviour following heating to a range of different temperatures

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By Ruth Saunders, Gavin Morris, Igor Chernyavsky, Rod Smallwood
| European Respiratory Journal Verified
ASM behaviour following heating to a range of different temperatures Ruth Saunders, Gavin Morris, Igor Chernyavsky, Rod Smallwood, Felicity Rose, Bindi Brook, Christopher Brightling European Respiratory Journal Sep 2016, 48 (suppl 60) PA3987; DOI: 10.1183/13993003.congress-2016.PA3987
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