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IIB-Sant Pau

As seen in: Nature, Wiley Online Library, Frontiers, Alzheimer's Research and Therapy, American Journal of Physiology, Ash Publications, International Journal of Cardiology, The European Heart Journal Podcast
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Articles

In memoriam: Ioanna Andreadou (1965-2025)

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By IIB-Sant Pau, Amsterdam UMC
| The European Heart Journal Podcast
PDF Split View Gemma Vilahur, Petra Kleinbongard, Coert J Zuurbier, on behalf of the Core Group of the COST Action EU-METAHEART (CA22169), In memoriam: Ioanna Andreadou (1965–2025), European Heart Journal, 2025;, ehaf066, https://doi.org/10.1093/eurheartj/ehaf066 Close It is with deep sadness that we pay tribute to Professor Ioanna Andreadou, who passed away on the night of 13 January 2025 at the age of 59. Ioanna was born in Athens, Greece.
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New COST Action ‘EUropean network to tackle METAbolic alterations in HEART failure’ (EU-METAHEART)

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By Clinic Würzburg, IIB-Sant Pau
| The European Heart Journal Podcast
Cardiovascular diseases (CVDs) are the main cause of morbidity and mortality in Europe, and heart failure (HF) is the terminal consequence of most CVD, making HF the largest disease burden in Europe. The prevalence of HF increases with age, and so does the prevalence of comorbidities. The most frequent comorbidities are chronic kidney disease, anaemia, and metabolic disorders, such as obesity and diabetes.
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Recombinant human soluble domain of CD39L3 and ticagrelor: cardioprotective effects in experimental myocardial infarction

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By IIB-Sant Pau, Liverpool Heart, Bioscience Cardiovascular
| The European Heart Journal Podcast
The ecto–nucleoside triphosphate diphosphohydrolases of the CD39 family degrade ATP and ADP into AMP, which is converted into adenosine by the extracellular CD73/ecto-5-nucleotidase. This pathway has been explored in antithrombotic treatments but little in myocardial protection. We have investigated whether the administration of solCD39L3 (AZD3366) confers additional cardioprotection to that of ticagrelor alone in a pre-clinical model of myocardial infarction (MI).
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