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Ila Tewari Jasra on Muck Rack

Ila Tewari Jasra

As seen in: Frontiers, BioRxiv
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Articles

Complete Suspension Differentiation of Human Pluripotent Stem Cells into Pancreatic Islets Using Vertical-Wheel Bioreactors

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By Nidheesh Dadheech, Nerea Cuesta-Gomez, Rena L. Pawlick, Ila Tewari Jasra
| BioRxiv
Abstract Advanced protocols to produce human pluripotent stem cell (SC)-derived islets show promise in functional, metabolic, and transcriptional maturation of cell therapy product to treat diabetes. Available protocols are either developed as complete planar (2D) or, in later stages, combined with suspension cultures (3D). Despite marked progress, both approaches have clear limitations for scalability, cell loss and batch to batch heterogeneity during differentiation.
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Mitochondrial regulation in human pluripotent stem cells during reprogramming and β cell differentiation

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By Tecnológico de Monterrey, A. M. James, Ila Tewari Jasra, Ila Tewari
| Frontiers
1 Introduction The introduction of the reprogramming factors Oct4, Sox2, Klf4, and c-Myc enable the reprogramming of adult somatic cells into induced pluripotent stem cells (iPSC) capable of self-renewal (1, 2). Autologous iPSCs hold promise for applications in precision health and regenerative medicine, disease modelling, and drug screening (3).
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