Ilde Rugolo on Muck Rack

Ilde Rugolo

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Articles

Identification of a Small Secretoneurin Derivative That Inhibits CaMKIIδ Activity

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By Xin Shen, Thea Parsberg Støle, Ilde Rugolo, Anna Bergan-Dahl
| Wiley Online Library Verified
1 Introduction Calcium (Ca2+)-calmodulin-dependent kinase II (CaMKII) is a serine/threonine kinase crucial for regulating Ca2+ signalling in various cell types, including cardiomyocytes. Among its isoforms, CaMKII delta (CaMKIIδ) is the predominant form expressed in the heart, where it plays an essential role in excitation-contraction coupling (ECC) by modulating calcium cycling [1, 2].
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