Ilenia Concetta Giardina

ABTS 2,2′-Azinobis (3-ethylbenzothiazoline-6-sulfonic acid) AAPH 2,2′-Azobis(2-methylpropionamidine) dihydrochloride BF bioaccessible fraction CI combination index CLDN1 claudin-1 gene CLDN3 claudin-3 gene CLDN4 claudin-4 gene GSTA1 glutathione S-transferase A1 gene HMOX-1 heme oxygenase 1 gene IBD inflammatory bowel diseases Keap1 kelch-like ECH-associated protein 1 LPS lipopolysaccharide NQO1 NAD(P)H quinone dehydrogenase 1 gene NF-κB nuclear factor kappa B NFE2L2 Nrf2 gene Nrf2 nuclear...

REFERENCES 1, , . Molecular mechanisms and pathophysiological significance of eryptosis. Int J Mol Sci. 2023; 24: 5079. 2, , , . Suicidal erythrocyte death in metabolic syndrome. Antioxidants. 2021; 10(2): 154. 3, , , , , . Enhanced suicidal erythrocyte death in acute cardiac failure. Eur J Clin Invest. 2015; 45(12): 1316–1324. 4, , , . Eryptosis—the neglected cause of anemia in end stage renal disease. Kidney Blood Press Res. 2017; 42: 749–760. 5, , . Physiology and pathophysiology of eryptosis.

1. Introduction Inflammatory bowel disease (IBD) is a group of relapsing, idiopathic and chronic inflammatory conditions affecting the gastrointestinal tract [1,2]. It is globally prevalent, with increasing incidence in the newly industrialized countries and strictly related to mass consumption of refined sugars and ultra-processed food items, typical of the Westernized diets [3].