Ilkin Yapici on Muck Rack

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Articles

Structural Insights into the Dynamics of Water in SOD1 Catalysis and Drug Interactions

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By Ilkin Yapici, Belgin Sever, Halilibrahim Ciftci, Arda Gorkem Tokur
| biorxiv.org
Abstract Superoxide dismutase 1 (SOD1) is a crucial enzyme that protects cells from oxidative damage by converting superoxide radicals into H2O2 and O2. This detoxification process, essential for cellular homeostasis, relies on a precisely orchestrated catalytic mechanism involving the copper cation, while the zinc cation contributes to the structural integrity of the enzyme.
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4D Crystallography Captures Transient IF1-Ribosome Dynamics in Translation Initiation

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By Ebru Destan, Esra Ayan, Ilkin Yapici, Shun Yokoi
| biorxiv.org
Abstract Initiation factor 1 (IF1) is one of multiple key ligands involved in the initiation of mRNA translation, a highly dynamic and carefully-orchestrated process. However, details surrounding IF1 transient interactions with the small 30S ribosomal subunit remain incompletely understood despite characterization of unbound and fully-bound 30S states.
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