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Inc. Ibaraki

As seen in: Royal Society of Chemistry
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Articles

Synthesis of the full-length hepatitis B virus core protein and its capsid formation

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By Kyoto Pharmaceutical, Shugo Tsuda, Keisuke Aoki, Inc. Ibaraki
| Royal Society of Chemistry Verified
Synthesis of the full-length hepatitis B virus core protein and its capsid formation† Chronic infection with hepatitis B virus (HBV) is a major cause of cirrhosis and liver cancer. Capsid assembly modulators can induce error-prone assembly of HBV core proteins to prevent the formation of infectious virions, representing promising candidates for treating chronic HBV infections.
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