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Correlative Cellular Mass Spectrometry Imaging and Amperometry Show Dose Dependent Changes in Lipid Composition and Exocytosis
The function of lipid-protein interactions on the regulation of exocytotic events is essential, especially in the context of neurodegenerative disease pathogenesis.1 The ubiquitin-proteasome system (UPS) is an evolutionarily conserved and meticulously orchestrated pathway.2 UPS mainly controls proteostasis and is involved in many cellular processes including lipid metabolism and exocytosis and as such is widely studied in the context of neurodegenerative diseases.1, 2 Specifically, disruption...
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