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Ingrid Judith Garberis on Muck Rack

Ingrid Judith Garberis

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Trastuzumab deruxtecan in metastatic breast cancer with variable HER2 expression: the phase 2 DAISY trial - Nature Medicine

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By Fernanda Mosele, Elise Deluche, Barbara Pistilli, Thomas Bachelot, Nathalie Droin, Maki Kobayashi, Marc Deloger, Marta Jiménez, Patricia L. Kannouche, Magali Lacroix-Triki, Véronique Diéras, Yoann Pradat, Ingrid Judith Garberis, Stergios Christodoulidis, Celine Mahier, Vianney Baris, Virginie Marty
| Nature Verified
Abstract The mechanisms of action of and resistance to trastuzumab deruxtecan (T-DXd), an anti-HER2–drug conjugate for breast cancer treatment, remain unclear. The phase 2 DAISY trial evaluated the efficacy of T-DXd in patients with HER2-overexpressing (n = 72, cohort 1), HER2-low (n = 74, cohort 2) and HER2 non-expressing (n = 40, cohort 3) metastatic breast cancer.
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