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Ingvi Gautsson

As seen in: Wiley Online Library, BioRxiv
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Articles

Target Genes of MITF in Projection Neurons of the Olfactory Bulb-A Role for MITF in Defining Gene Expression of Middle Tufted Cells

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By Fatich Mechmet, Ingvi Gautsson, Eirikur Steingrimsson, Snævar Sigurðsson
| Wiley Online Library Verified
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that supports the findings of this study are available in the supplementary material of this article. Peer Review The peer review history for this article is available at https://www.webofscience.com/api/gateway/wos/peer-review/10.1111/ejn.70293.
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MITF regulates gene expression in middle tufted neurons and other projection neurons of the olfactory bulb

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By Fatich Mechmet, Snaevar Sigurdsson, Eirikur Steingrimsson, Ingvi Gautsson
| BioRxiv
Abstract The microphthalmia-associated transcription factor (MITF) is a master transcription factor in melanocytes and plays equally important roles in mast cells. It is required for the generation, differentiation, and function of these cell types in vertebrates. Mitf is also expressed in the projection neurons of the olfactory bulb (OB), the mitral and tufted (M/T) cells. Loss of Mitf leads to neuronal hyperactivity in primary M/T cells but the general function of Mitf in neurons is unknown.
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