Filename Description acel70698-sup-0001-FigureS1-S6.pdfPDF document, 3.6 MB Figure S1: Validation of Cdkn2a (p16) RNA-ISH specificity using p16Ink4a total knockout kidneys. Representative RNAscope in situ hybridization images for Cdkn2a (p16) (red) with DAPI (blue) in kidneys from p16Ink4a total knockout (KO) and wild-type (WT) mice, shown at 10× and 40× magnification. Figure S2: Fibrosis and tubular injury increase with age and Gene Ontology enrichment associated with Cdkn2a (p16) expression.
