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Metabolic Diseases

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Articles

Transcriptome expression profiles and regulatory networks in patients with heart failure following myocardial infarction

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By Metabolic Diseases
| TechTrends
Background The molecular mechanisms underlying heart failure (HF) following myocardial infarction (MI) (HF-MI) remain incompletely understood, and discoveries from whole-transcriptome profiling hold significant promise for disease prevention and treatment. Methods Whole-transcriptome sequencing was performed on whole blood from post-MI patients with and without HF to analyze differentially expressed mRNAs, lncRNAs, and circRNAs, along with functional enrichment analysis.
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Metabolic implications of hepatic, pancreatic and abdominal adipose tissue depots in Asian Indians across normoglycaemia, prediabetes and type 2 diabetes

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By Surya Prakash, Irshad Ahmad, Metabolic Diseases
| TechTrends
Misra A, Sattar N, Ghosh A, Nassar M, Jayawardena R, Gupta R (2025) Type 2 diabetes in South Asians. BMJ 390:e079801. https://doi.org/10.1136/bmj-2024-079801 Article CAS PubMed Google Scholar Misra A, Vikram NK, Ghosh A et al (2025) Revised definition of obesity in Asian Indians living in India. Diabetes Metab Syndr 19(1):102989.
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Genetic basis of Asian diabetes

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By Takafumi Ojima, Toshimasa Yamauchi, Metabolic Diseases
| Wiley Online Library Verified
INTRODUCTION The onset of diabetes is shaped by both inherited genetic factors and environmental exposures.1, 2 The proportion of influence from environmental factors versus genetic factors in diabetes differs across diabetes groups. Diseases caused by genetic factors are generally categorized into two distinct disease concepts: monogenic diseases and polygenic diseases, also known as complex diseases or common diseases3 (Figure 1).
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