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Metabolic Diseases

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Articles

A novel clinical FIT model predicts prognosis of unresectable hepatocellular carcinoma treated with TACE combined with lenvatinib and PD-1 inhibitors therapy

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By Metabolic Diseases
| Frontiers in Immunology
Abstract Background: Transcatheter arterial chemoembolization (TACE) with lenvatinib and programmed death-1 (PD-1) inhibitors therapy (triple therapy) demonstrated encouraging efficacy for unresectable hepatocellular carcinoma (uHCC). This study developed and validated a novel prognostic model to evaluate prognosis of uHCC patients with triple therapy, and identify patients who may benefit from triple therapy.
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Siemens Healthineers and Novo Partner to Expand Blood-Based Testing for MASLD and MASH

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By Metabolic Diseases
| Clinical Lab Products Verified
The collaboration aims to broaden clinical access to non-invasive diagnostics like the ELF blood test to detect liver disease before serious complications develop. Siemens Healthineers and Novo have announced a collaboration focused on advancing care for patients living with metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive form, metabolic dysfunction-associated steatohepatitis (MASH).
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BRD4780-mediated clearance of mutant alpha-1-antitrypsin involves the autophagiclysosomal pathway

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By Metabolic Diseases
| zenodo.org
Published September 21, 2026 | Version v1 1. Institute of Clinical and Experimental Medicine 2. Research Unit for Rare Diseases, Department of Pediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic 3.
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