Metabolic Diseases
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Transcriptome expression profiles and regulatory networks in patients with heart failure following myocardial infarction
Background The molecular mechanisms underlying heart failure (HF) following myocardial infarction (MI) (HF-MI) remain incompletely understood, and discoveries from whole-transcriptome profiling hold significant promise for disease prevention and treatment. Methods Whole-transcriptome sequencing was performed on whole blood from post-MI patients with and without HF to analyze differentially expressed mRNAs, lncRNAs, and circRNAs, along with functional enrichment analysis.
Metabolic implications of hepatic, pancreatic and abdominal adipose tissue depots in Asian Indians across normoglycaemia, prediabetes and type 2 diabetes
Misra A, Sattar N, Ghosh A, Nassar M, Jayawardena R, Gupta R (2025) Type 2 diabetes in South Asians. BMJ 390:e079801. https://doi.org/10.1136/bmj-2024-079801 Article CAS PubMed Google Scholar Misra A, Vikram NK, Ghosh A et al (2025) Revised definition of obesity in Asian Indians living in India. Diabetes Metab Syndr 19(1):102989.
Diagnostic Options in Graves' or Non-Graves' Thyrotoxicosis: A Review for Clinical Practice
GD Graves' disease TRAbs thyrotropin receptor antibodies US ultrasonography TMNG toxic multinodular goiter AIT amiodarone-induced thyrotoxicosis AI artificial intelligence. 1 Introduction The prevalence of overt thyrotoxicosis is approximately 1%, with Graves' disease (GD) accounting for 60–70% of cases and representing the most common cause of thyrotoxicosis [1-3].
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