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Metabolomics Point out the Effects of Carfilzomib on Aromatic Amino Acid Biosynthesis and Degradation
3. Discussion This study aimed to enrich the existing knowledge on Cfz-induced nephrotoxicity by the metabolomics prospective, performing RP chromatographic analysis, as a complementary step to Barla et al.’s published workflow [1]. Metabolomics deals with thousands of compounds, therefore, the combination of different separation methodologies offers more opportunities for ‘good performance’ for a larger number of metabolites.
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