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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Epigenetic fingerprints link early-onset colon and rectal cancer to pesticide exposure
Abstract The incidence of colorectal cancer (CRC) is rising rapidly in people younger than 50 years. Although this increase parallels shifts in lifestyle and environmental factors—collectively termed the exposome—whether these are indeed linked to the development of early-onset CRC (EOCRC) remains uninvestigated.
Cibisatamab and FAP-4-1BBL in microsatellite-stable colorectal cancer: a phase 1b trial
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Abstract We evaluated cibisatamab, a carcinoembryonic antigen (CEA)-directed CD3 T cell-engaging bispecific antibody, in combination with FAP-4-1BBL, a fibroblast activation protein (FAP)-targeted 4-1BB ligand providing tumor-localized co-stimulation, in an open-label phase 1b dose-escalation study in patients with microsatellite-stable (MSS) metastatic colorectal cancer (mCRC) progressing after two or more prior therapies.
By Ignacio Melero, Tamara Tanos, Emiliano Calvo Aller, Camilla Qvortrup, Marloes van Dongen, Iosune Baraibar, Seung-Hoon Beom, Fiona Thistlethwaite, Maria Garcia, Maria García, María García, Victoria Woodcock, Pablo Umaña, Christine McIntyre, Lining Chen, Christian Heichinger, Heather Hinton, Tulun Saylan, Iakov I Davydov, Ernesto Guarin, Axel Boehnke, Victor Moreno
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Nature
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Current and Emerging Treatment Paradigms in Colorectal Cancer: Integrating Hallmarks of Cancer
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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