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Ipek Isik Gonul on Muck Rack

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The effect of adipocyte–macrophage crosstalk in obesity-related breast cancer in: Journal of Molecular Endocrinology Volume 62 Issue 3 (2019)

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By Ayse Basak Engin, Atilla Engin, Ipek Isik Gonul, Cameron MehlM
| bioscientifica.com
Introduction Obesity is mainly dependent on excessive fat accumulation in the regional adipose tissues. In obese individuals, more adipocytes release more adipocytokines. Large breast volume is proportional to the fat storage in the visceral and intermuscular depots in obese premenopausal women (Janiszewski et al. 2010). Postmenopausal patients with high visceral fat area have significantly shorter distant disease-free survival than premenopausal patients in breast cancer series (Iwase et al. 2016).
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