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Iqball Faheem on Muck Rack

Iqball Faheem

As seen in: Wiley Online Library, ACS Publications
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Articles

Multifunctional Mycobacterial Topoisomerases with Distinctive Features

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By Iqball Faheem, Valakunja Nagaraja, E. Lynn, Chen Shin-Fu
| ACS Publications
Special Issue Published as part of ACS Infectious Diseases special issue “Combating Tuberculosis: Obstacles, Innovations, and the Road Ahead”. Introduction Click to copy section linkSection link copied! Topoisomerases are a universal class of enzymes that are essential in controlling cellular functions.
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Distinct subunit architecture and assembly pattern of DNA gyrase from mycobacteria

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By Richa Gupta, Iqball Faheem, Valakunja Nagaraja
| Wiley Online Library Verified
Abstract DNA gyrase, the sole negative supercoiling type II topoisomerase, is composed of two subunits, GyrA and GyrB, encoded by the gyrA and gyrB genes, respectively, that form a quaternary complex of A2B2. In this study, we have investigated the assembly of mycobacterial DNA gyrase from its individual subunits, a step prerequisite for its activity.
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