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IRCCS Multi Medica

As seen in: Oxford University Press (OUP), Frontiers, Biomed Central (BMC), JAMA (The Journal of the American Medical Association), JAMA: Journal of the American Medical Association, The Lancet, Atherosclerosis, International Journal of Cardiology, Journal of Science and Medicine in Sport, European Journal of Obstetrics & Gynaecology and Reproductive Biology and
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Articles

Validation of the Ontario Protocol Assessment Level (OPAL) Tool for Assessing Clinical Trial Complexity and Supporting Workforce Planning in the Italian Clinical Research Context

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By IRCCS Multi Medica, Sesto San Giovanni
| TechTrends
Study Aim, Design, Setting, and Eligibility Criteria This study aimed to adapt and validate the OPAL tool within the Italian clinical research context. A cross-sectional design was employed, involving multiple Italian research institutions, including IRCCSs, university hospitals, and public healthcare centers. All ongoing and completed clinical trials at participating sites were eligible for inclusion.
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Impact of aging on CD146 + mesenchymal stromal cells-mediated regulation of bone marrow CD34 + hematopoietic stem/progenitor cell mobilization

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By IRCCS Multi Medica, Pathology “Nicolae Simionescu”, Miruna Larisa
| Frontiers
Abstract Background: The study of age-associated changes in the bone marrow (BM), a key organ for hematopoiesis and immune regulation, is crucial to understanding inflammatory processes linked to cardiovascular diseases. Notably, aging is associated with impaired mobilization of BM-derived cardioprotective CD34+ hematopoietic stem/progenitor cells (HSPCs), resulting in a lower frequency in the circulation and poorer cardiovascular outcomes.
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Web discussions on cardiovascular diseases: pre-COVID-19 evaluation and impact of the COVID-19 pandemic - Web listening analysis in the Italian population | BMC Public Health | Full Text

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By Maria Rita, Roberto Enrico, Dipartimento Cardiovascolare, IRCCS Multi Medica
| Biomed Central (BMC)
According to Web analysis by Google Trends methodology, we observed that, over the whole timeframe of the analysis (February 2018- July 2020), “Tumore” (cancer) was the most searched word on Google within the set of diseases taken into consideration (vaccines, influenza, diabetes, stroke, heart failure, heart attack). However, during the COVID-19 pandemic timeframe, “Influenza” and “Vaccino” (vaccine) were the most searched words (Fig. 1A and B). Google trends searches on 6 diseases in Italy.
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