İrem Nisa Sezer

Abstract Cerebral carbon dioxide (CO2) vasoreactivity (CVR), defined as the dilatory capacity of cerebral vessels in response to CO2, has pathophysiological importance and is clinically relevant. Reservoir–excess pressure analysis (REPA) of arterial blood pressure (ABP) waveforms, which estimates the pressure-buffering (reservoir) capacity of large arteries, provides contemporary insights beyond standard ABP measures by encompassing global arterial compliance and vascular tone.

How do we really get to know someone? And how many times do we meet the same person throughout life? I think we’re often so focused on understanding the people around us that we forget to understand ourselves first. Can we truly know anyone else before we’ve met ourselves? Then the real question becomes: how do we meet ourselves—and how many times in a lifetime do we get that chance? Hello, I’m Nisa.

Introduction Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive, life-threatening condition characterized by extracellular amyloid deposition in the interstitial spaces of the heart.1 ATTR-CM can be classified into the hereditary form which is associated with mutations in the TTR gene (ATTRv), and the wild-type form (ATTRwt) which is late-onset, with a male predominance.