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Basophil Activation Test as Biomarker of Severity and Threshold of Allergic Reactions to Cow's Milk During Oral Food Challenges
1 Introduction Cow's milk allergy (CMA) is the most common food allergy worldwide, recently reported to affect about 6% of the general population in Western countries [1]. It resolves in about 60% of children by school age but can persist throughout life. Cow's milk is one of the most common causes of fatalities from food-induced anaphylaxis, alongside peanut and other nuts [2-4].
Basophil activation test as predictor of severity and threshold of allergic reactions to egg
AUC area under the curve BAT basophil activation test BAS basophil DBPCFC double-blind placebo-controlled food challenge KU/L kilounits per litre OVM ovomucin SI stimulation index sIgE specific IgE sens sensitivity spec specificity tIgE total IgE 1 INTRODUCTION Food allergy negatively affects the lives of allergic children and their families limiting the diet and causing anxiety and social restrictions due to the need to avoid the allergen and the absence of a curative treatment.1 This is...
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