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Irina Ribeiro Bas on Muck Rack

Irina Ribeiro Bas

As seen in: Wiley Online Library, Science Magazine
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Articles

HSPCs and T reg cells cooperate to preserve extramedullary hematopoiesis under chronic inflammation

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By Valdemar Priebe, Peter Sheridan Dodds, Mohammad A Saad, Maria L. Kuzmina, Srdjan Grusanovic, Jiří Březina, Flavian Thelen, Karolina Vanickova, Mirko Milosevic, Irina Ribeiro Bas, Nataliia Pavliuchenko, Sarka Ruzickova, Jakub Rohlena, Dominik Filipp, Katerina Rohlenova, César Nombela-Arrieta, Tomas Brdicka, Meritxell Alberich-Jorda
| Science Magazine Verified
Abstract Hematopoietic stem and progenitor cells (HSPCs) are localized within specialized niches of the bone marrow (BM). However, during hematological disorders or infections, the functionality of these cells in the BM is compromised, leading to extramedullary hematopoiesis (EMH). Chronic inflammation drives EMH, yet its impact on HSPCs outside the BM is poorly understood.
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Hematopoietic stem cells undergo a lymphoid to myeloid switch in early stages of emergency granulopoiesis

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By Karolina Vanickova, Mirko Milosevic, Irina Ribeiro Bas, Monika Burocziova
| embopress.org
Introduction Granulocytes represent an essential part of the innate immune system and serve as major effector cells responsible for the control of bacterial and fungal pathogens (Nauseef & Borregaard, 2014). In steady-state conditions, the production of granulocytes is known as granulopoiesis, while during severe infections emergency granulopoiesis is taking place.
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Hematopoietic stem cells undergo a lymphoid to myeloid switch in early stages of emergency granulopoiesis

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By Karolina Vanickova, Mirko Milosevic, Irina Ribeiro Bas, Monika Burocziova
| Wiley Online Library Verified
Introduction Granulocytes represent an essential part of the innate immune system and serve as major effector cells responsible for the control of bacterial and fungal pathogens (Nauseef & Borregaard, 2014). In steady-state conditions, the production of granulocytes is known as granulopoiesis, while during severe infections emergency granulopoiesis is taking place.
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