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Articles by I.S. Boon
Design of photoactivatable methylene blue-bufalin conjugate for GPX4-targeted degradation to induce ferroptosis-like death in breast cancer therapy
Venenum bufonis is a precious traditional Chinese medicine extracted from the dried secretions of toads from the Bufonidae family, specifically Bufo gargarizans Cantor or Duttaphrynus melanostictus Schneider [1]. It is widely used in clinical practice across Asian countries for treating various diseases.
Adopting Machine Learning Auto-Segmentation Into Radiotherapy Workflow
Madam — We thank Harrison et al. [] for distilling the advances and challenges of machine learning approaches to radiotherapy auto-segmentation. The radiotherapy workforce and oncology services remain highly stretched in the UK, with predicted shortfalls in the future. The potential of artificial intelligence to mitigate this via radiotherapy auto-segmentation is immense, but is rapidly evolving in development [] and remains nascent clinical adoption [].
Advances of Cancer Genomics in Oncology Care
Madam — Cancer genomics, driven by liquid biopsy and next generation sequencing (NGS) of tumour, is rapidly being adapted into UK oncology pathways. This is consistent with the National Health Service (NHS) long-term plan to provide world class oncology care []. NGS allows rapid sequencing of nucleotides, potentially offering clinical utility to oncologists.
Price is What You Pay, Value is What You Get
Madam — We read the thought-provoking research by Marta et al. [ 1 Marta G.N. Ramiah D. Kaidar-Person O. Kirby A. Coles C. Jagsi R. et al. The Financial Impact on Reimbursement of Moderately Hypofractionated Postoperative Radiation Therapy for Breast Cancer: An International Consortium Report [published online ahead of print, 2020 Dec 22]. ] on the international variation in financial reimbursement as a result of hypofractionated breast radiotherapy.
The COVID-19 Pandemic as a Catalyst for a National Cancer Imaging Repository: Answering the Topol Review
This paper is only available as a PDF. To read, Please Download here.
Effectiveness of Clinical Examination in Cancer Surveillance: New Paradigm to Cancer Survivorship Beyond the COVID-19 Pandemic
I.S. Boon I.S. Boon Correspondence Address for correspondence: I.S. Boon, Department of Clinical Oncology, Leeds Cancer Centre, St James's Institute of Oncology, Leeds, UK.
Effect of the COVID-19 Pandemic on Cancer Clinician Decision Making: Known Knowns and Known Unknowns
Expand allCollapse all Madam — COVID-19 is a global pandemic [1x[1]World Health Organisation. Coronavirus disease 2019 (COVID-19) situation report – 75. ; 4 April 2020 ()https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports. Google ScholarSee all References1] and poses a significant challenge to cancer patients. Cancer-specific mortality rates are well established.
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