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In Vivo Tracking and 3D Mapping of Cell Death in Regeneration and Cancer Using Trypan Blue
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Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer - Nature Communications
Abstract Hyperactivation of YAP/TAZ, the Hippo pathway downstream effectors, is common in human cancer. The requirement of YAP/TAZ for cancer cell survival in preclinical models, prompted the development of pharmacological inhibitors that suppress their transcriptional activity.
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