Isadora Serraglio Fortes

1 Introduction Cancer is a global public health challenge and includes more than 100 different types of diseases. These diseases are characterized by the development of abnormal cells with deregulated growth rate, lack of differentiation, and dysregulation of apoptosis factors that allow cancer to proliferate. Despite the high cure rate for childhood cancer [1], pediatric cancer continues to be the major cause of death among children and young adults between 1 and 19 years.