Iva Loureiro Hoffmann on Muck Rack

Iva Loureiro Hoffmann

As seen in: MDPI
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11p15 Epimutations in Pediatric Embryonic Tumors: Insights from a Methylome Analysis

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By Juliana Silveira Ruas, Mayara Ferreira Euzébio, Thais Junqueira, Iva Loureiro Hoffmann
| MDPI
1. Introduction During normal development, epigenetic modifications are remodeled to define embryo patterning and for organ and cell-type specification; then, upon terminal differentiation, they are maintained to sustain cell identity. When disrupted, the epigenome may play a role in cancer initiation and progression [1].
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