Ivan Michele Aniceto

1 Introduction Medication-related osteonecrosis of the jaw (MRONJ) is a complex and often debilitating condition that has recently emerged as a significant focus of scientific research. Owing to the relative novelty of the disease, definitions and classification systems have been proposed between European (Bedogni et al. 2024) and American frameworks (Khosla et al. 2007) (Ruggiero et al. 2022).