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Articles

Patients with Multiple Myeloma Have Increased Co-Expression of HLA-E and HLA-DR Molecules on T-Lymphocytes and Monocytes in Peripheral Blood

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By Ivan Pavlovich Skachkov, Alina Aktanova, Olga Boeva, Vera Denisova
| preprints.org
Background/Objectives: Multiple myeloma (MM) is characterized by complex interactions between tumor plasma cells and the tumor microenvironment, in which immune escape mechanisms play a key role. Non-classical major histocompatibility complex (MHC) molecules HLA-E and HLA-G are receptors capable of suppressing the activity of NK cells and T lymphocytes. However, their expression on immune cells in oncology, particularly in MM, remains poorly understood.
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CD5 Expression by Innate Lymphoid Cells Type 2 in Multiple Myeloma Before and After Hematopoietic Stem Cell Transplantation

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By Ekaterina Pashkina, Olga Boeva, Vera Denisova, Ivan Pavlovich Skachkov
| preprints.org
This version is not peer-reviewed. Ekaterina Aleksandrovna Pashkina  *,Olga Sergeevna Boeva,Ivan Pavlovich Skachkov,Vera Vasilevna Denisova,Vladimir Aleksandrovich Kozlov Ekaterina Aleksandrovna Pashkina  *,Olga Sergeevna Boeva,Ivan Pavlovich Skachkov,Vera Vasilevna Denisova,Vladimir Aleksandrovich Kozlov Submitted: 08 December 2025 You are already at the latest version Multiple myeloma is a malignant tumor disease that affects plasma cells and is one of the most common tumors of lymphoid origin.
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