Ivar Grytten

14 hours ago A recent routine autopsy yielded a first-of-its-kind medical finding—a 78-year-old man who lived his entire life with three penises. But given the anatomical complexities, it’s entirely possible he never even knew of his own extremely rare condition. Supernumerary penile formation, aka multiple male …

Abstract Structural variation is known to play an important and often overlooked role in regulating disease and traits, but accurately detecting structural variants from sequencing data has traditionally been difficult. However, recent improvements in high-quality genome assembly along with methodological advancements in pangenome creation have opened up the landscape for methods that use such pangenomes for structural variant calling and genotyping.