Ivo Ludwig Hofacker on Muck Rack

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Articles

tRNA expression and modification landscapes, and their dynamics during zebrafish embryo development

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By Maria Waldl, Anastasia Chugunova, Tom Rappol, Ivo Ludwig Hofacker
| biorxiv.org
Abstract tRNA genes exist in multiple copies in the genome of all organisms across the three domains of life. Besides the sequence differences across tRNA copies, extensive post-transcriptional modification adds a further layer to tRNA diversification. Whilst the crucial role of tRNAs as adapter molecules in protein translation is well established, whether all tRNA are actually expressed, and whether the differences across isodecoders play any regulatory role is only recently being uncovered.
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