Izabela Barańska

Chiral hydroxylamines, defined by their characteristic N–O bond, are pivotal structural motifs in bioactive molecules, including the agrochemical Clomazone and pharmaceuticals such as Zileuton and Spiropidion (Figure 1A). (1) This N–O bond endows these compounds with unique pharmacokinetic properties, such as enhanced metabolic stability and improved target binding affinity.

Special Issue Published as part of The Journal of Organic Chemistry special issue “Physical Organic Chemistry: Never Out of Style”. 1. Introduction Click to copy section linkSection link copied! Fluorescent dyes are widely used across various technological fields, requiring optimization of their fundamental properties for specific applications. Several strategies can be employed to tune the properties of the emitting molecules.

Download Hi-Res ImageDownload to MS-PowerPointCite This:Org. Lett. 2024, XXXX, XXX Izabela Barańska Nicolaus Copernicus University in Torun, Faculty of Chemistry, 7 Gagarin Street, Torun 87-100, Poland , Borys Ośmiałowski Nicolaus Copernicus University in Torun, Faculty of Chemistry, 7 Gagarin Street, Torun 87-100, Poland , Katarzyna Rafińska Nicolaus Copernicus University in Torun, Faculty of Chemistry, 7 Gagarin Street, Torun 87-100, Poland , and * Cite this: Org. Lett. 2024, XXXX, XXX .