J. Christopher Luke

Abstract A cone-cylinder-flare model with sharp and blunt nosetips was tested at the AFRL Mach-6 Ludwieg Tube at a 0\(^{\circ }\) angle of attack. Surface-pressure fluctuation measurements, high-speed schlieren images, and surface-heat-transfer measurements were taken to study instability and transition as related to an axisymmetric separation bubble downstream of each nosetip. Three nosetip radii were tested, nominally sharp (0.1 mm), 1 mm, and 5 mm.

Early Childhood Education Journal, Apr 2023 This is a preview of a remote PDF: https://link.springer.com/content/pdf/10.1007/s10643-023-01466-y.pdf Essien, Idara, Wood, J. Luke. , Early Childhood Education Journal, 2023, pp. 1-12, DOI: 10.1007/s10643-023-01466-y

The generation of a functional, self-tolerant T cell receptor (TCR) repertoire depends on interactions between developing thymocytes and antigen-presenting thymic epithelial cells (TECs). Cortical TECs (cTECs) rely on unique antigen-processing machinery to generate self-peptides specialized for T cell positive selection. In our current study, we focus on the lipid kinase Vps34, which has been implicated in autophagy and endocytic vesicle trafficking.