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Articles by J Wang
How to grade an AI agent's output before it ships
AI agents now produce work — code, support replies, claims decisions, research memos, documents — faster than any team can review it. The uncomfortable part: most models are aligned to be helpful and agreeable, so an agent tends to approve its own output. At any real scale, that means unreviewed agent work reaches production. The fix isn't "review everything by hand" (you can't) or "trust the model" (it's the thing being checked).
Outcomes and management of invasive procedures in participants with hemophilia A post gene therapy a post hoc analysis of the GENEr81 phase III trial
Outcomes and management of invasive procedures in participants with hemophilia A post gene therapy a post hoc analysis of the GENEr81 phase III trial
Point of care ultrasound and subxiphoid window reduce uncertainty in the management of potential dualcavity injuries in patients with torso stab wounds
Point of care ultrasound and subxiphoid window reduce uncertainty in the management of potential dualcavity injuries in patients with torso stab wounds
Management cost of acute respiratory infections in older adults in China: A systematic review and meta-analysis — JOGH
Acute respiratory infection (ARI), including acute upper respiratory and lower respiratory infections, is a common respiratory infectious illness and poses a significant public health challenge worldwide. While ARI can affect individuals across all age groups, the health impact is notably more substantial among older adults.
Gastrointestinal: Annular pancreas: duodenal ampulla cancer
We reported a 71-year-old female patient. The patient was hospitalized seven times for acute pancreatitis and with an abdominal magnetic resonance imaging (MRI) (Fig. 1a) and magnetic resonance cholangiopancreatography (MRCP) suggesting abnormalities in the anatomy of the pancreas, which was an annular pancreas (Fig. 1b). The patient has been admitted to the hospital again. Contrast enhanced CT examination suggested duodenal ampulla cancer (Fig. 1c,d).
Changing-look NLS1 galaxies, their detection with SVOM, and the case of NGC 1566
Changing-look NLS1 galaxies, their detection with SVOM, and the case of NGC 1566 Mots clés active galactic nuclei Seyfert galaxies NGC 1566 broad-line region supermassive black holes space mission SVOM accretion disks optical spectra X-ray spectra Fichier principal universe-10-00061-v3.pdf (646.4 Ko) Télécharger le fichier Origine : Fichiers éditeurs autorisés sur une archive ouverte
Pteropox infection in a juvenile grey‐headed flying fox (Pteropus poliocephalus)
Conflicts of interest and sources of funding The authors declare no conflicts of interest or sources of funding for the work presented here. References 1, , et al. A novel poxvirus isolated from an Egyptian fruit bat in Israel. Vet Med Sci 2020; 6: 587–590. 2, , et al. Genomic characterization of a novel poxvirus from a flying fox: evidence for a new genus? J Gen Virol 2016; 97: 2363–2375. 3, , et al. Novel poxvirus in big brown bats, northwestern United States. Emerg Infect Dis 2013; 19: 1002.
[Analysis the effect of cytokine-induced killer cells combined with mFOLFOX6 regimen in chemotherapy for advanced colorectal cancer]
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[TFG-ROS1 fusion positive inflammatory myofibroblastoma of uterus: report of a case]
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ANTI-INFLAMMATORY EFFECT OF BIOLOGIC THERAPY IN PATIENTS WITH PSORIATIC DISEASE COMPARED WITH TREATMENT WITH NON-BIOLOGIC DMARDS: A PROSPECTIVE COHORT FDG-PET STUDY
BACKGROUND Psoriatic arthritis (PsA) and cutaneous psoriasis (PsO) are linked with an increased risk of adverse cardiovascular events. We hypothesized that central vascular inflammation on F-18-fluorodeoxyglucose (FDG) positron emission tomography (PET) in the ascending aorta would improve in these patients following therapy with biologic agents compared to PsO patients receiving non-biologic therapy and non-inflammatory control patients.
IMPACT OF DOOR-TO-FUROSEMIDE TIME ON CLINICAL OUTCOMES IN PATIENTS WITH ACUTE HEART FAILURE
BACKGROUND Rapid diagnosis and initiation of therapeutic interventions is a quality measure in acute heart failure (AHF) care. However, the impact of earlier treatment is unclear. We examined the association between door-to-furosemide (D2F) time and clinical outcomes in patients presenting to hospital with AHF. METHODS AND RESULTS CAN-HF is a Canadian multi-centre, retrospective, observational study of patients hospitalized with AHF.
The acid-labile subunit (ALS) of the 150 kDa IGF-binding protein complex: an important but forgotten component of the circulating IGF system
The insulin-like growth factors-I and -II (IGFs) are involved in a wide array of cellular processes such as proliferation, prevention of apoptosis, and differentiation. Most of these effects are mediated by the IGF-I receptor, although at higher IGF concentrations the insulin receptor can also be activated. As the expression of both the IGFs and their receptors is widespread, IGFs are thought to have autocrine/paracrine modes of actions also, particularly during foetal life.
Developmental expression of the cyclo-oxygenase-1 and cyclo-oxygenase-2 genes in the peri-implantation mouse uterus and their differential regulation by the blastocyst and ovarian steroids
Cyclo-oxygenase (COX) is a rate-limiting enzyme that converts arachidonic acid to prostaglandins (PGs) and exists in two isoforms, COX-1 and COX-2. In the rodent, increased uterine vascular permeability at sites of blastocyst apposition is one of the earliest prerequisite events in the implantation process. This event is preceded by generalized uterine edema and luminal closure, and coincides with the initial attachment reaction between the trophectoderm and luminal epithelium.
The Cost-Utility of Solifenacin in the Treatment of Patients with Overactive Bladder in China
To evaluate the cost-utility of Solifenacin compared with Tolterodine in the treatment of overactive bladder syndrome (OAB) in China.
Patient-Reported Utility on Pembrolizumab (Pembro) and Ipilimumab (Ipi) among Ipi Naïve Patients with Advanced Melanoma
To assess change in health utility at 12 weeks (W) among advanced melanoma patients treated with pembro or ipi in Keynote-006 (NCT01866319).
Cost-Effectiveness of Pembrolizumab (Keytruda®) Versus Ipilimumab in Patients with Advanced Melanoma in Canada
To assess the cost-effectiveness of pembrolizumab compared with ipilimumab in patients with unresectable or metastatic melanoma (advanced melanoma) previously untreated with ipilimumab, from the perspective of a Canadian publicly funded health care system.
Cost Effectiveness of Pembrolizumab (Keytruda®) Versus Ipilimumab in Patients with Advanced Melanoma in the United States
To evaluate the cost-effectiveness of pembrolizumab versus ipilimumab in patients with advanced melanoma who are previously untreated with ipilimumab from US Medicare perspective.
Indirect Comparison Of Pembrolizumab To Vemurafenib And Dabrafenib Monotherapy For First-Line Treatment Of Advanced Melanoma In Braf Mutation Positive Ipilimumab Naïve Patients - Value in Health
To estimate the survival outcomes of pembrolizumab relative to BRAF inhibitors vemurafenib and dabrafenib for the first line (1L) treatment of advanced-stage melanoma in BRAF mutation positive patients who are naïve to treatment with ipilimumab.
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