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Articles by Jacoby GA
Comparative in vitro antibacterial activity of herbal extracts from Piper betle L., Bauhinia scandens L. and Chromolaena odorata against Staphylococcus aureus , Escherichia coli and Pseudomonas aeruginosa
Sokom Kong conceived and designed the experiments, performed the experiments, analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the article, and approved the final draft. Jaturong Wongsanit conceived and designed the experiments, performed the experiments, authored or reviewed drafts of the article, performed the herbal and sample collection and preparation, and approved the final draft.
Novel monoclonal antibodies for immunodetection of AmpC β-lactamases
Novel monoclonal antibodies for immunodetection of AmpC β-lactamases 1Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius, Lithuania 2ArcDia International Ltd, Turku, Finland 3Institute of Biosciences, Life Sciences Center, Vilnius University, Vilnius, Lithuania DOI 10.7717/peerj.20036 Academic Editor Travis Beddoe Subject Areas Biotechnology, Immunology Keywords β-lactamase detection, CMY β-lactamases, CMY-34, ELISA, TPX assay, Monoclonal antibodies, Lateral flow...
Advances in drug resistance and resistance mechanisms of four colorectal cancer-associated gut microbiota
Advances in drug resistance and resistance mechanisms of four colorectal cancer-associated gut microbiota 1Institute of Zoonosis, College of Public Health, Zunyi Medical University, Zunyi, Guizhou, China 2Xingyi City Disease Prevention and Control Center (Municipal Health Supervision Station), Xingyi, Guizhou, China 3Institute of Gastrointestinal, Affiliate Hospital of Zunyi Medical University, Zunyi, Guizhou, China 4Key Laboratory of Maternal & Child Health and Exposure Science of Guizhou...
Infectious Diseases Society of America 2024 Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections
Antimicrobial-resistant (AMR) infections are a global crisis. Internationally, approximately 1.3 million deaths were estimated to be directly attributable to AMR pathogens in 2019 [1]. In the United States, AMR pathogens caused more than 2.8 million infections and over 35 000 deaths annually from 2012 through 2017, according to the Centers for Disease Control and Prevention (CDC) Antibiotic Resistance Threats in the United States Report [2].
Evolving resistance landscape in gram‐negative pathogens: An update on β‐lactam and β‐lactam‐inhibitor treatment combinations for carbapenem‐resistant organisms
CONFLICT OF INTEREST STATEMENT J.L.K. reports grants from Merck & Co, Inc, Shionogi, Entasis, the United States Food and Drug Administration, Biomeriuex, Roche, consulting fees and payment or honoraria for lectures from Shionogi. C.K. has received consulting fees and honoraria for lectures from Shionogi, Pfizer and Gilead, and reports grants from the DAMP and Joachim Herz Foundations. REFERENCES 1, , , .
Antimicrobial resistance profiles of Escherichia coli isolated from clinical and environmental samples: findings and implications
Antibiotics have been a cornerstone in treating infectious diseases, thereby improving patients’ quality of life and life expectancy.1 Their discovery marked one of the greatest achievements in the medical field.2 However, their overuse and misuse have contributed to the emergence of antimicrobial resistance (AMR), which occurs when microorganisms resist the lethal effects of antimicrobials.3–8 AMR is a public health threat affecting humans, animals and the environment; therefore; addressing...
In vitro activity of cefepime/taniborbactam and comparator agents against Gram-negative bacterial bloodstream pathogens recovered from patients with cancer
Patients with cancer are prone to develop frequent bacterial infections, especially during chemotherapy-induced neutropenia.
What are the optimal pharmacokinetic/pharmacodynamic targets for β-lactamase inhibitors? A systematic review
β-Lactam (BL) antibiotics are one of the widely used classes of antimicrobials to battle the war against bacterial infections.
Clinical, microbiological and genomic characterization of Gram-negative bacteria with dual carbapenemases as identified by rapid molecular testing
Carbapenem resistance in Gram-negative bacteria occurs due to several mechanisms, which include carbapenemase production, diminished outer membrane permeability, and overexpression of efflux pump, among others.1 Production of carbapenemases, however, is the most significant mechanism of resistance since carbapenemases are typically encoded by genes in mobile genetic elements that can be horizontally transferred within species and genera.2 Infections with carbapenem-resistant Enterobacterales...
A multicentre study to determine the in vitro efficacy of flomoxef against extended-spectrum beta-lactamase producing Escherichia coli in Malaysia
A multicentre study to determine the in vitro efficacy of flomoxef against extended-spectrum beta-lactamase producing Escherichia coli in Malaysia 1Jeffrey Cheah School of Medicine and Health Science, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia 2School of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia 3Department of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia 4Department of Medical Microbiology and Immunology, Faculty of...
Characterization of antimicrobial‐resistant Escherichia coli causing urinary tract infections in dogs: Passive surveillance in Saskatchewan, Canada 2014 to 2018
Abstract Background Urinary tract infections (UTIs) are common in dogs and can be caused by multidrug‐resistant Escherichia coli (E coli). Objective To describe the frequency and mechanisms of antimicrobial resistance (AMR) among E coli causing UTIs in dogs in Western Canada during a 4‐year surveillance period. Animals Urine from 516 dogs. Methods From November 2014 to 2018, 516 nonduplicate E coli isolates from the urine of dogs were collected from a diagnostic laboratory.
Rapid detection of the plasmid-mediated quinolone resistance determinant AAC(6′)-Ib-cr in Enterobacteriaceae by MALDI-TOF MS analysis
Objectives: Rapid detection of the plasmid-mediated quinolone resistance determinant AAC(6?)-Ib-cr in Enterobacteriaceae by measuring acetyltransferase activity against fluoroquinolones by MALDI-TOF MS analysis.
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