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Jacqueline Barlow on Muck Rack

Jacqueline Barlow

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As seen in: Medium, BioRxiv
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Articles

G-quadruplex stabilization induces DNA breaks in pericentromeric repetitive DNA sequences in B lymphocytes

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By Kalkidan Ayele, Jacqueline Barlow, Irina Waisertreiger, Mehad Hilal Elshaikh
| BioRxiv
Abstract DNA secondary G-quadruplex (G4) structures can impair and even obstruct the DNA replication. Defects in processing G4 structures are associated with replication stress, a common property of both B cell cancers and hyperproliferative premalignant cells. Genome instability arising from replication stress is a hallmark of cancer and strongly contributes to the chromosome rearrangements in B cell cancers.
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Distal super-enhancer drives aberrant CXCL13 in Cancer cells driving growth and p53 dysregulation via CXCR5-CXCL13 axis

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By Santosh Kumar Gothwal, Pieta K. Mattila, Jacqueline Barlow
| BioRxiv
Abstract The CXCL13 chemokine plays a crucial role in guiding B cell migration to the light zones (LZs) during the germinal center (GC) reaction. While CXCL13 expression is absent in most cell types, aberrant amplification of the CXCR5-CXCL13 signaling is observed in various cancers, including germinal center-derived B-lymphomas (GCDBL), colorectal adenocarcinoma (COAD), and liver hepatocellular carcinoma (LIHC).
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Typefaces

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By Jacqueline Barlow
| Medium
The nonsense word 'Hamburgevons', which is used for testing typefaces, rendered using seven fonts. JamesLucas, CC BY-SA 4.0 <https://creativecommons.org/licenses/by-sa/4.0>, via Wikimedia Commons Mudlarking by Lara Maiklem is an enchanting account of the author's exploration and gentle excavation of the foreshore of the Thames, whose tidal waters regularly draw back and reveal treasures to those who know how to look.
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