Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Jad Othman
Elevated levels of TNF and its targets characterize better-risk older acute myeloid leukemia patients
To the Editor: Acute myeloid leukemia (AML) is a heterogeneous cancer. The incidence rate of AML increases while the survival rates decrease with age (median age of diagnosis 69 years) [1]. Intensive combination chemotherapy remains an upfront treatment option [2]; however, some AML patients over the age of 60 (aged AML; aAML) are unfit for intensive treatment and/or fail to achieve remission [3]. A key step in treatment selection is risk classification.
MRD Status in NPM1 Mutated AML Should be a Part of the Selection of Patients for Transplant in First Remission
december 2023 Listen to Dr. Jad Othman about his study, presented at the ASH 2023 meeting, which focused on the use of MRD status to determine the necessity of allogeneic stem cell transplant in NPM1 mutated AML patients. Combining data from the UK NCRI AML17 and AML19 studies, the research revealed that MRD negativity after chemotherapy did not warrant a transplant, whereas MRD positive patients benefited significantly.
FLT3 inhibitors as MRD-guided salvage treatment for molecular failure in FLT3 mutated AML - Leukemia
Abstract Patients with FLT3-mutated AML have a high relapse rate and suboptimal outcomes. Many have co-mutations suitable for measurable residual disease (MRD) monitoring by RT-qPCR and those destined to relapse can be identified by high or rising levels of MRD, called molecular failure. This provides a window for pre-emptive intervention, but there is little evidence to guide treatment. The use of FLT3 inhibitors (FLT3i) appears attractive but their use has not yet been evaluated.
Time to add gemtuzumab ozogamicin to intensive chemotherapy for NPM1-mutated acute myeloid leukaemia?
Save citation to file Format: Add to My Bibliography Your saved search Name of saved search: Search terms: Frequency: Which day? Which day? Report format: Send at most: Send even when there aren't any new results Optional text in email: Create a file for external citation management software
Time to add gemtuzumab ozogamicin to intensive chemotherapy for NPM1-mutated acute myeloid leukaemia?
Perhaps no other drug in malignant haematology has had such a convoluted clinical development pathway as gemtuzumab ozogamicin, an antibody–drug conjugate targeting CD33. Gemtuzumab ozogamicin was approved 23 years ago for relapsed acute myeloid leukaemia, before being voluntarily withdrawn.
Long‐term outcomes of corticosteroid graft versus host disease prophylaxis in peripheral blood allogeneic haemopoietic stem cell transplant: a comparative cohort analysis
Introduction Haemopoietic stem cell transplant (HSCT) is an effective treatment for life-threatening malignant and non-malignant diseases in adults and children. The effective prevention of acute and chronic graft versus host disease (GVHD) without compromising HSCT outcomes by increasing the risk of other complications of HSCT, particularly infection and relapse, is key to the success of transplantation.
Tattoo Pigment-Induced Granulomatous Lymphadenopathy Mimicking Lymphoma
Case Report: A 30-year-old woman presented to our clinic reporting a 2-week history of bilateral axillary lumps noted on self-examination. She had no fever, night sweats, weight loss, or pulmonary symptoms. She had a history of cluster headaches and had had breast augmentation surgery at age 19 years. Her only medication was an oral contraceptive pill. She was a nonsmoker with no relevant family history.
Tattoo Pigment-Induced Granulomatous Lymphadenopathy Mimicking Lymphoma
Case Report: A 30-year-old woman presented to our clinic reporting a 2-week history of bilateral axillary lumps noted on self-examination. She had no fever, night sweats, weight loss, or pulmonary symptoms. She had a history of cluster headaches and had previously had breast augmentation surgery at age 19 years. Her only medication was an oral contraceptive pill. She was a nonsmoker with no relevant family history.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Jad
Contact Jad, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack