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Jaeseoung Choi on Muck Rack

Jaeseoung Choi

As seen in: Nature
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Articles

Gut microbiome modulation by Veillonella ratti induces resistance to EAE pathogenesis via microbe-derived metabolites

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By Joon-Young Park, Subin Moon, Chan Hee Lee, Tae-Young Kim, Mi-Na Kweon, Keon-Hyoung Song, Dong-Woo Lee, Myung Hee Nam, Soo-Jong Hong, Eun-Young Lee, Seong Ran Jeon, Ho-Yeon Song, Bong-Soo Kim, Yun Kyung Lee, Panida Sittipo, Eunike Tiffany, Jaeseoung Choi
| Nature Verified
Abstract The progression of multiple sclerosis (MS) is potentially influenced by the microbiome. Elucidating host–microbiome interactions in MS may aid in developing microbiome-based applications; however, these interactions remain unclear. Here, we aimed to elucidate how Veillonella ratti MHL0042, isolated from human infant feces, modulates neuroinflammation and disease severity in experimental autoimmune encephalomyelitis, a murine MS model. Whole metagenomic sequencing revealed that V.
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