Jaeyop Lee on Muck Rack

Jaeyop Lee

As seen in: The Journal of Immunology
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Articles

Defects in Long-Term APC Repopulation Ability of Adult Human Bone Marrow Hematopoietic Stem Cells (HSCs) Compared with Fetal Liver HSCs

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By Grace Nauman, Nichole Danzl, Jaeyop Lee, Chiara Borsotti
| The Journal of Immunology
Key Points aBM HSCs expand in aBM-transplanted mice. aBM CD34+ cells show less durable APC reconstitution than FL CD34+ cells. Cytokine/niche support and intrabone injection improve APC reconstitution from aBM. Abstract Immunodeficient mice reconstituted with immune systems from patients, or personalized immune (PI) mice, are powerful tools for understanding human disease.
Open in Who Shared Issue with article?

Defects in Long-Term APC Repopulation Ability of Adult Human Bone Marrow Hematopoietic Stem Cells (HSCs) Compared with Fetal Liver HSCs

|
By Nichole Danzl, Grace Nauman, Jaeyop Lee, Chiara Borsotti
| The Journal of Immunology
Grace Nauman, Nichole M. Danzl, Jaeyop Lee, Chiara Borsotti, Rachel Madley, Jianing Fu, Markus A. Hölzl, Alexander Dahmani, Akaitz Dorronsoro Gonzalez, Éstefania Chavez, Sean R. Campbell, Suxiao Yang, Prakash Satwani, Kang Liu and Megan Sykes J Immunol March 21, 2022, ji2100966; DOI: https://doi.org/10.4049/jimmunol.2100966 Key Points aBM HSCs expand in aBM-transplanted mice. aBM CD34+ cells show less durable APC reconstitution than FL CD34+ cells.
Open in Who Shared Issue with article?
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