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Jagjit Singh Bhamra

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Articles

Long-term HIV-1 remission achieved through allogeneic haematopoietic stem cell transplant from a CCR5 Δ32/Δ32 sibling donor

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By Anders Myhre, Malin Holm Meyer-Myklestad, Hanne Hestdal Gullaksen, Ole S. Søgaard, Martin Tolstrup, Maria Salgado, María C Salgado, Javier Martinez-Picado, Mona Holberg-Petersen, Anna Juhl, Mariane H Schleimann, Jesper D. Gunst, Astrid Thomsen, Katie Fisher, Jagjit Singh Bhamra, Anne-Marte Bakken Kran, Bente Halvorsen, Anne Ma Dyrhol-Riise, Dag Henrik Reikvam, Pål Aukrust, Tobias Gedde-Dahl, Tuva Børresdatter Dahl, Mari Kaarbø, Marius Trøseid
| Nature Verified
Abstract Only few cases of human immunodeficiency virus (HIV) remission have been reported after allogeneic haematopoietic stem cell transplantation (HSCT), mostly involving stem cell donors with the homozygous CCR5Δ32 (CCR5Δ32/Δ32) mutation, which confers resistance to CCR5-tropic HIV-1. Here we report the case of a 63-year-old man in off-treatment HIV remission, 5 years after HSCT with a CCR5Δ32/Δ32 sibling donor for myelodysplastic syndrome.
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