Jaime L Speiser

Objectives Identifying patients in the emergency department (ED) at higher risk for in-hospital mortality can inform shared decision making and goals-of-care discussions. Electronic health record systems allow for integrated multivariable logistic regression (LR) modeling, which can provide early predictions of mortality risk in time for crucial decision making during a patient's initial care.

Recent advances in technology have allowed for the expanded use of hybrid closed-loop insulin pump therapy and automated insulin delivery systems for the management of diabetes mellitus. We assessed the outcomes of introducing Tandem t:slim X2 with the Control-IQ technology in a general endocrine clinic. Data from 66 adults with type 1 (n = 61) and type 2 (n = 5) diabetes mellitus were aggregated for analysis.

This was a nested cohort study within a retrospective database (the Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database) of patients with septic shock. Data was collected from 28 medical centers in Canada, the USA, and Saudi Arabia between 1996 and 2015. The details of the study design and data collection were described in a previous paper [9]. Approval was obtained from the Institutional Review Boards of all participating institutions.