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Jake Barker

As seen in: Wiley Online Library, Royal Society of Chemistry, New Atlas, VAVEL, Devex, Outkick, Microbiology Research, Clipperholics, Tyne Warp: VAVEL UK's Newcastle United Podcast (Podcast)

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Articles

Integrated computational and experimental design of fluorescent heteroatom-functionalised maleimide derivatives

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By Jake Barker, Gareth Richings, Yujie Xie, Julia Y. Rho
| Royal Society of Chemistry Verified
Integrated computational and experimental design of fluorescent heteroatom-functionalised maleimide derivatives The bottom-up design and synthesis of organic molecular species with tailored photophysical properties stands as an important challenge to both computational and experimental chemical science. Overcoming this challenge presents the potential to usher in new tools and approaches to improve our ability to develop new technologies, such as molecular sensors and attuned molecular switches.
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Substituted Maleimides: Self‐Reportable Linkers and Tags in Bioconjugation, Material Science, and Nanotechnology

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By Jake Barker, Joshua Tibbetts, Calum Ferguson
| pericles.pericles-prod.literatumonline.com
Substituted maleimides are customisable fluorescent linkers and probes with adaptable reactivity and optical properties. Their compact nature and tunability has led to their use in various applications. For example, their solvatochromic properties offer real-time feedback on linking chemistry and environmental changes, essential for applications in material labelling, drug delivery, and nanoparticle functionalization.
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Substituted Maleimides: Self‐Reportable Linkers and Tags in Bioconjugation, Materials Science, and Nanotechnology

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By Jake Barker, Joshua Tibbetts, Calum Ferguson, Yujie Xie
| Wiley Online Library Verified
1 Introduction Maleimides are unsaturated four-carbon cyclic imides, one of organic synthesis's most important nitrogen-containing heterocyclic motifs.
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