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Jake Baroch

As seen in: National Human Genome Research Institute
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Articles

Webinar: Ancient Genetic Clues into Modern Human Disease

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By Alexander Arguello, Ismail Safi, Jake Baroch
| National Human Genome Research Institute
Event Details Oct 15, 2024, 10:00 AM — 12:00 PM Background In its 2020 Strategic Vision, the National Human Genome Research Institute (NHGRI) identified the need to “elucidate the genetic architecture of the majority of human diseases and traits.” Traditionally used to illuminate human evolution and demography, ancient (>500 years old) and historical (<500 years old) DNA is now being applied towards the origins and biology of human disease.
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Advances in the Genetic Architecture of Complex Human Traits

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By Alexander Arguello, Ismail Safi, Jake Baroch
| National Human Genome Research Institute
Interdependencies across scales of biological, social, and ecological organization may confound modern-day genetic association studies limiting their interpretation and application both within and between individuals, families, and populations. Large-scale genetic, genomic, and phenotypic data now provide an opportunity to develop novel approaches that embrace and leverage this real-world complexity and improve our understanding of phenotypic variation.
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