Jakobus Burggraaf on Muck Rack

Jakobus Burggraaf

As seen in: Journal of Nuclear Medicine
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Articles

Intraoperative Molecular Fluorescence Imaging of Pancreatic Cancer by Targeting Vascular Endothelial Growth Factor: A Multicenter Feasibility Dose-Escalation Study

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By Marjory Koller, Arantza Farina Sarasqueta, Evelien W. Duiker, Jakobus Burggraaf
| Journal of Nuclear Medicine Verified
Tumor visualization with near-infrared fluorescence (NIRF) imaging might aid exploration and resection of pancreatic cancer by visualizing the tumor in real time. Conjugation of the near-infrared fluorophore IRDye800CW to the monoclonal antibody bevacizumab enables targeting of vascular endothelial growth factor A. The aim of this study was to determine whether intraoperative tumor-specific imaging of pancreatic cancer with the fluorescent tracer bevacizumab-800CW is feasible and safe.
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