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Jakuei Fu on Muck Rack

Jakuei Fu

As seen in: Nature
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Articles

Supramolecular nanofiber stabilization of microdroplets enables ultra-sensitive virus infection analysis

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By Noriyuki Uchida, Atsuya Yaguchi, Haruka Umezawa, Naito Ishimoto, Michiko Tajiri, Satoko Akashi, Takuya Seki, Go Watanabe, Ayano Yoshida, Daisuke Yoshino, Hirotsugu Hiramatsu, Masaki Okumura, Tomohide Saio, Hiroyuki Noji, Young-Ho Lee, Sam-Yong Park, Takahiro Muraoka, Shiori Kondo, Kazuyoshi Muranishi, Haruka Kawabata, Genki Higuchi, Jakuei Fu, Takanobu Takenouchi
| Nature Verified
Abstract Aqueous two-phase system (ATPS) droplets in cells act as fluidic microreactors by concentrating biomacromolecules. Inspired by this phenomenon, dextran-rich microdroplets formed in an ATPS with polyethylene glycol have been explored as artificial microreactors for sensitive detection and spatiotemporal control of biochemical reactions. However, the rapid fusion of the microdroplets into bulk phase separation has limited practical applications of this approach.
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