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De-Escalation Therapy in Metastatic Prostate Cancer: A Retrospective Study on Intermittent ADT and ARPI Combination Treatment.
Androgen deprivation therapy (ADT) combined with an androgen receptor pathway inhibitor (ARPI) is standard care for metastatic prostate cancer (mPCa), but prolonged treatment causes clinical and financial toxicity. The efficacy of intermittent treatment in the ARPI era remains unclear. We evaluated outcomes after planned treatment cessation following a deep response to ADT plus ARPI.
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