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Jameel Barnawi on Muck Rack

Jameel Barnawi

As seen in: Nature, MDPI
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Articles

Potential DPP-IV inhibitors for type 2 diabetes mellitus: an integrated computational and experimental pipeline

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By Mohnad Abdalla, Mohamed T. M. Nemr, Abdullah Y Hamadi, Nouf Omar Alafaleq, Khalid M. Sumaily, Ahmed H. Mujamammi, Jameel Barnawi, Ziyad M Althafar, Yongsheng Ge, Guohua Liu, Guiyu Lin, Essa M. Sabi, Amr Ahmed El-Arabey
| Nature Verified
Abstract Dipeptidyl peptidase-IV (DPP-IV) inhibition remains a cornerstone therapeutic strategy for managing type 2 diabetes mellitus (T2DM) by prolonging endogenous incretin hormone activity. However, developing next-generation inhibitors with optimized pharmacokinetic profiles and enhanced target stability remains an ongoing challenge.
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