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James Greenan-Barrett on Muck Rack

James Greenan-Barrett

As seen in: The Lancet, medRxiv, European Respiratory Journal
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Articles

Single-gene transcripts for subclinical tuberculosis: an individual participant data meta-analysis

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By James Greenan-Barrett, UCL Respiratory, Simon C Mendelsohn
| The Lancet Verified
Introduction Despite global efforts, tuberculosis is a leading cause of morbidity and mortality worldwide, with 10·6 million cases and 1·3 million deaths in 2022, and a disproportionate burden among disadvantaged communities.1,2 In response to increased recognition of the spectrum of tuberculosis, the International Consensus for Early Tuberculosis (ICE-TB) group developed a framework to classify disease states in 2024.
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The end of the road for blood RNA biomarkers as triage tests for symptomatic pulmonary tuberculosis among spontaneous sputum producers?

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By James Greenan-Barrett
| European Respiratory Journal Verified
Footnotes Conflict of interest: M. Noursadeghi holds a patent in relation to blood transcriptomic biomarkers of tuberculosis. The remaining authors report no other conflicts of interest. Support statement: R.K. Gupta and M. Noursadeghi are supported by NIHR Biomedical Research Funding to UCL and UCLH. In addition, R.K. Gupta is funded by National Institute for Health Research (NIHR303184) and M. Noursadeghi by the Wellcome Trust (207511/Z/17/Z).
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Resolution of tuberculosis blood RNA signatures fails to discriminate persistent sputum culture positivity after eight weeks of anti-tuberculous treatment

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By Claire Calderwood, James Greenan-Barrett, Jennifer K Roe
| European Respiratory Journal Verified
Footnotes This manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article. Conflict of interest: Nick H. Kim Conflict of interest: C. J.
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